Why Of Mice and Men?

I think that Steinbeck chose 'Of Mice and Men' as the title for his book because he wanted to relate to the poem written by Robert Burns. In the book, Lennie, George and Candy have a plan to retire to a nice place of their own in the country side however their plans are turned upside down just as the mouses's house was destroyed in the poem.

In relationship to real life and Steinbeck's book, it suggests that no plan is fool-proof and one can not be completely prepared for the future.